The Buena Vista exit sign on Highway 1 in Watsonville was knocked down late Wednesday night when the male driver of a Freightliner big rig lost control and crashed.
Julieta Trenado of the California Highway Patrol said it is not known why he lost control at 10:44 p.m. while traveling south on Highway 1, north of Buena Vista Drive.
At one point a trailer dump bed tumbled into the overhanging exit sign. The 65-year-old Watsonville man suffered major injuries.
Alcohol/drugs do not appear to be a factor in this collision, Trenado said.
The CHP kept traffic moving around the crash site. The road was cleared by 2:30 a.m.